Definition of: deplete

(di·plēt′) v.t. ·plet·ed, ·plet·ing
1. To reduce or lessen, as by use, exhaustion, or waste.
2. To empty, or partially empty: to deplete the treasury.
3. Med. To lessen or remove the contents of (an overcharged organ or vessel), as by purging or bloodletting. [<L depletus, pp. of deplere <de- not + plere fill]